Product ID:PYRIDINE FREE CHLOROFORM, H7972-6
MSDS Date:05/12/1986
FSC:6630
NIIN:00N069048
MSDS Number: CBJWW

SERAGEN INC

INDIANAPOLIS, IN 46206
US

Emergency Phone: 317-266-2000

Info Phone: 317-266-2000

Preparer: MICHAEL J. SULLIVAN

Cage: JO299

SERAGEN INC

1210 INDIANAPOLIS, IN 46206 US

Telephone: 317-266-2000

Cage: JO299

CHLOROFORM (SARA 302/313) (CERCLA)

CAS: 67-66-3

RTECS: FS9100000

OSHA PEL 50 PPM, C

ACGIH TLV: 10 PPM

EPA Report Quantity: 10 LBS

DOT Report Quantity: 10 LBS

LD50 LC50 Mixture:NONE SPECIFIED BY MANUFACTURER.
Routes of Entry: Inhalation:YES Skin:NO Ingestion:NO
Reports of Carcinogenicity:NTP:YES IARC:YES OSHA:NO
Health Hazards Acute and Chronic:HEADACHE, NAUSEA, DIZZINESS,
DRUNKENNESS. CHLOROCARBON MATLS HAVE PRODUCED SENSIT OF MYOCARDIUM
TO EPINEPHRINE IN LAB ANIMALS & COULD HAVE SIMILAR EFT IN HUMANS.
ADRENOMIMETICS (E. G., EPINEPHRINE) MA Y BE CONTRAINDICATED EXCEPT
FOR LIFE-SUSTAINING USES IN HUMANS ACUTELY/CHRONICALLY EXPOS TO
CHLOROCARBONS .
Explanation of Carcinogenicity:CHLOROFORM:IARC MONOGRAPHS, SUPP, VOL 7,
PG 152, 1987:GRP 2B. NTP 7TH ANNUAL RPT ON CARCINS, 1994:ANTIC TO
BE (SUPDAT)
Effects of Overexposure:SEE HEALTH HAZARDS.
Medical Cond Aggravated by Exposure:NONE SPECIFIED BY MANUFACTURER.

First Aid:INGEST:CALL MD IMMED . INHAL:REMOVE TO FRESH AIR. SUPPORT
BRTHG (GIVE O*2/ARTF RESP) . EYES:IMMED & CONTINUOUSLY FLUSH
W/FLOWING WATER FOR AT LST 15 MINS. SKIN:IMMED & CONTINUOUSLY FLUSH
W /FLOWING WATER. NOTE TO MD:OVEREXP TO MANY OF CHLORINATED SOLVS,
ESP IF ACCOMPANIED BY ANOXIA, MAY TEMPORARILY INCR CARDIAC
IRRITABILITY. MAINTAIN ADEQ OXYGENATION UNTIL RECOVERY. AVOID (SUPP
DATA)

Flash Point Method:CC
Extinguishing Media:MEDIA SUITABLE FOR SURROUNDING FIRE .
Fire Fighting Procedures:USE NIOSH/MSHA APPRVD PRESS DEMAND SCBA & FULL
PROT EQUIP . SLIGHT FIRE HAZARD WHEN EXPOSED TO HIGH HEAT:
OTHERWISE PRACTICALLY NON-FLAMMABLE.

Spill Release Procedures:NONE SPECIFIED BY MANUFACTURER.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:HANDLE W/REASONABLE CARE. AVOID
BREATHING VAPORS.
Other Precautions:NO SMOKING IN AREA OF USE. DO NOT USE IN GENERAL
VICINITY OF ARC WELDING, OPEN FLAMES OR HOT SURFACES. HEAT &/OR UV
RADIATION MAY CAUSE FORMATION OF HCL &/OR PHOSGENE .

Respiratory Protection:IN AREAS OF HIGH CONCENTRATION, WEAR NIOSH/MSHA
APPROVED SELF CONTAINED BREATHING APPARATUS.
Ventilation:LOCAL EXHAUST &/OR MECHANICAL (GENERAL).
Protective Gloves:RUBBER GLOVES.
Eye Protection:ANSI APPROVED CHEM WORKERS GOGGS .
Other Protective Equipment:EYE WASH FOUNTAIN & DELUGE SHOWER WHICH MEET
ANSI DESIGN CRITERIA .
Work Hygienic Practices:NONE SPECIFIED BY MANUFACTURER.
Supplemental Safety and Health
EXPLAN OF CARCIN:CARCINOGEN. ANIMAL:LIVER/KIDNEY TUMORS, CNS EFTS.
FIRST AID PROC:SYMPTOMINETIC AMINES, SUCH AS EPINEPHRINE, WHICH MAY
PRECIPITATE ARRHYTHMIAS.

Boiling Pt:B.P. Text:142F,61C
Melt/Freeze Pt:M.P/F.P Text:-82F,-64C
Vapor Pres:160 @ 20C
Vapor Density:4.13
Spec Gravity:1.49
Solubility in Water:INSOLUBLE
Appearance and Odor:COLORLESS LIQUID; ETHEREAL ODOR.
Percent Volatiles by Volume:100%

Stability Indicator/Materials to Avoid:YES
CAUSTIC SODA ASH & OTHER STRONG BASES (VIOLENT EXOTHERMIC RXN),
ALUMINUM & HOT METALS.
Hazardous Decomposition Products:HCL, PHOSGENE .

Waste Disposal Methods:DISPOSAL MUST BE I/A/W FEDERAL, STATE & LOCAL
REGULATIONS .

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.